I don't think so. We see this speculation come up with a lot of the popular MTG planes, but I just don't think most of them are likely.
Bloomburrow would have been a good choice, but we've seen nothing on that front.
Duskmourn is also weird because of the weird 80's vibes. It's not just a horror themed set, but a horror movie themed set. There are a ton of references to thinks like Gremlin's, IT, Children of the Corn, Ghost Busters.. A lot of MTG players have lamented the set for being mostly great, flavorfully speaking. A lot of folks loved all the horror elements, like Valgavoth and the living house, but then were turned off by the inclusion of cheerleaders, jocks, and television sets.
Fortunately the set mechanics were good, the limited environment was good, and enough of the flavor was good that the set was generally well regarded, but it probably won't go down as an all time favorite.
I don't know if it'd be able to clear that hurdle in TTRPG space. I would imagine that WOTC figures that most people looking for the kind of game that would exist in this setting would probably turn towards something like Call of Cthulhu.
With that said, a while back Rosewater had mentioned that the set slated for Q1 2026 (Code name: Yachting) was going to be a return to Arcavios, the plane where Strixhaven is. Whether or not that's being pushed back with the new Universes Beyond in standard thing (The Return to Lorwyn set scheduled for the end of next year was pushed back, so I could see everything moving down the chain a little) is another question.. But I could see them trying to do another tie-in there..
What would be really cool is if WOTC would have their creative teams work on just small adventures set in some of these settings. They don't all need full-fledged hard cover core books, but I bet a little module set in Bloomburrow where the players are all turned into various woodland critters and need to hunt down and destroy a Calamity Beast before being able to return to their normal world would go over well.