Your first character with a Prestige Class

[the Jester]

My first prc was the 1e bard- you had to play a fighter who turned thief who turned to druid training, which made one a bard.

In 3e, I've almost exclusively dmed; but in the epic campaign I play in, I run Yolanda, a wizard/alienish/planeshifter (what a natural combo!) We started at 21st level, though, so it isn't like I worked my way up to the prcs...

Yolanda is, to the best of my recall, the only prc pc I've played since 3e started.

 

[Arkham]

My first PrC was the Sacred Flame from Dragon Magazine,
the issue with Radiant Servant of Pelor and such...
( With errata, so no unlimited Burning Hands etc... )

She started as a cleric with the Magic and Fire domains in a
game that initially only had two players, with only one PC each.
So we both played something as flexible as possible. The other
player was a Druid. Lots of healing available.

 

[mhacdebhandia]

The first Third Edition character I played was a sorcerer/alienist; his backstory implied that his potential for magical aptitude - his parents were both lay devotees of Boccob - drew the attention of entities from the Far Realm, from whom he drew his sorcerous power. Eventually he found a cabal of mages who taught him how to contact them more directly . . .

 

[Graybeard]

One of my current PC's is a Sorcerer/Fatespinner. I had discussed it with my DM in advance and it seemed like a natural fit for this character. He always (nearly always) rolled well on saving throws so it was a good fit.