Surprisingly, the Curse of Strife is still around (instead of being retconned as a myth like the orcs' Curse of Ruin), but now it is not specific to goblinoids or inflicted automatically upon birth. The goblins, hobgoblins, and bugbears were created by the Strife Empreror (aka Bane) and many in southern lands have been afflicted with the Curse of Strife via the Bestow Curse spell when cast by clerics of the Strife Emperor, but clerics of any race can inflict the Curse of Strife on anyone. Goblins, hobgoblins, and bugbears are also mentioned to have increasingly moved from isolated communities to join the populations of Tal'dorei's towns and cities.
The Ruiner (aka Gruumsh) worshiping cult called the Ravagers is still around, and the artwork depicts a goblin and orc (who were described as making up the majority of the Ravagers before), but no reference is made to orcs or goblins in the text and it is stated that anyone can be a follower of the Ruiner (though the Ruiner himself is still described as orc like). For the most part orcs are portrayed in this book more as former rivals of goliaths.
Drow surprisingly still have it pretty rough, with about the only major change being that drow explorers and worshipers of the Luxon from Wildemount are trying to infiltrate Lolthite drow society to try and find pieces of the Luxon and to convert the Tal'dorei drow to worship of the new god.
As a side note, the races section also mentions characters of mixed-ancestry beyond half-elves and half-orcs. An illustration of an elf-dragonborn and an orc-dwarf is included, though the book gives only general advice on working with a DM to create a mixed-ancestry character.