I voted "yes," because it is a revised edition, in effectively the same way that 3.5e was a revised edition of 3.0. Is it absolutely perfectly the same kinds of change? No, not really. But that is far and away the most comparable thing we have. It is, by conscious intent, backwards-compatible with adventures of yesteryear--just as 3.5e was compatible with 3.0 adventures. It is not directly compatible with old content, which requires varying levels of adaptation and, as the people making it have said, old content is probably not going to work quite right, you're on your own--much like adapting things like Savage Species (which never got a 3.5e version).
It's smaller than the jump between 2e and 3e, between 3e and 4e, or between 4e and 5e. I would say "it is bigger than the jump between original 4e and Essentials 4e," but there is no jump there, the two are the same game. I don't have enough familiarity with 1e to be able to compare it with the jump between 1e and 2e, otherwise I would include that one too.
This is the new system going forward. It can run any adventure written for the old system. It can adapt--with varying degrees of comfort--rules from the original version. It changes a lot of things, some big, some small, some subtle, some dramatic. It is, genuinely, replacing the original version in terms of player-facing content; naturally, as with any "replacement" in a TTRPG, fans are completely free to do whatever they want at their own tables, but the rules will be written with the expectation that people use the revised base, not the original base.
It is a revised edition. The fact that WotC is too afraid of the consequences of admitting this plain and simple fact does not, in any way, diminish that it is the plain truth--no more than any other ad campaign that tries to pretend that something is other than what it is. WotC is free to speak whatever marketing gobbledygook they wish. Those with eyes to see and ears to hear will know.