IMO, the point about whether WotC is making the game easier or harder for DMs to run the game and challenge players is going to be less dependent on the DMG, and more dependent on the Monster Manual. Generally when I’ve seen people say WotC is “hostile” to DMs, they’re usually referring to this point: how much effort does the DM have to put into making an encounter that will challenge players across the various tiers of play?
It always seems to come down to the monsters. How much damage can they do? Do they have enough HP or are they going to eat it in a single round? Are they going to be stunlocked or banished immediately even though they’re your BBEG? Yes, there’s ways to mitigate that but that’s where the increased effort comes in…the amount of work that the DM has to do to make it challenging. It’s why some of the best 3rd party products have been monster accessories as of late.