While technically possible, I really don't think Pathfinder will EVER eclipse D&D as the industry leading RPG, EVER. Not because D&D is better, as that's pretty subjective, but because D&D is the OG RPG.
Pathfinder is a beloved and best-selling RPG and probably will continue to be for quite some time, but it isn't serious competition to D&D.
Things change
Before getting hung up on that, keep in mind that it is not a yes/no question. The brand recognition issue is entirely about shades of grey. D&D can be number 1 for a very long time and still be worth a lot less than its full potential.
But D&D will always be #1 to *you and the people you know*. The people who will be leading the economy 20 years from now have not heard of RPGs yet.
But in even shorter term than that, the "OG" gamers are doing nothing but aging. A few more will be gone (from the market at least) by the end of the month. And new players who have never heard of RPGs will discover it this month. They will hear of D&D. But they will also hear of PF. And neither one will have a special place in the heart as the original. They are both "old school" games as far as the new player is concerned.
At the same time, people do evolve in their focus. Not everyone is you and history is loading with people who were shocked when society passed them by.
History is is also loaded with brand kings that faded into being just part of the pack. (or even complete oblivion).
It can happen quite suddenly.
Also, don't get hung up on Pathfinder. Pathfinder is big in play right now, but there could be another game (or three) that take over the industry. There is constantly a push of innovation and ideas and a few of them are actually good. The leader must always stay in the now and ahead of the pack.
Also, it can just take one major technology change for the entire marketplace to change their view of what they want, and being OG suddenly becomes either irrelevant, or even an albatross.
The presumption that these things can not change, that brands are not fragile in the overall market is really short-sighted and naive.