We have had some success with this group, but mind you I think out of all the DM's of Age of Worms I've killed the most characters.
1. PC's don't complement one another. My players don't work together, they tend to make a character that is fun to play/roleplay first, strategy second. The problem with this is large for this particular campaign.
2. Players tend to avoid playing clerics. You will need a cleric, possibly a healing specialist.
3. My PC's have never had to run away so often before. They have the kamakaze hero trait, all of them.
CN Warlock Diabolus
CN Barb/Rog Dwarf
NE Clr/Wiz elf, going Mystic Theurge
CN Sword-and-board human fighter
TN GMNPC Halfling cleric
I probably can't even list the amount of dead characters. Its about 15 now.
We are halfway through the lizard caverns and I've had a session where no-one died. We all rejoiced. I'm vaguely uncertain about the "I'll never roll but change the result at will" now.
But hell it's fun. My players really appreciate success now.