No it has nothing at all to do with the PC being blind, it is because the description of the spell says "a target you can see" or the action reaction says an enemy that you can see. That applies regardless of the reason you can not be seen and it is specifically seperate from the blinded condition. You could be behind a wall and you can't use it, someone can step between you and the target and hold up a sheet, and you know exactly where he is but you can't "see" him and therefore you can't use the spell that requires you to see the target.Yes, because the PC is Blind.Yes, because the PC is Blind.
Finally this illustrates that being blinded is not intended to eliminate being targeted BECAUSE many spells, including many spells that require an attack roll do NOT say anything about the enemy needing to be seen, while others, including many that do not require an attack roll state that the enemy must be seen to use the spell. Regardless of whether or not you do a perception check you can not use the latter spell against someone invisible (or if your blinded). It is being unseen, not being hidden, or not not knowing where the person is that renders the latter null and void. This strongly implies that spells that do not have that wording do not require the target to be seen otherwise the wording would be redundant and inconsistent.
Rule in your game how you want, but don't try to pretend it is RAW.But how I rule things in my game is irrelevant to your game.
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