I'm in the solidly neutral camp.
For one thing, I already have a game that I enjoy, and I'm not going to "squee" at the announcement of "the new shiny." I don't necessarily enjoy something just because it is new. In fact... WotC is going to have a tough sell on me--my feeling was that 4E was due around 2010 or so, I'm not all that interested in a new version right now.
I also can't imagine how they are going to design an edition that appeals to all players. When it comes down to brass tacks, some firm decisions about the game will have to be made and someone will feel left by the wayside. If the system is modular and customizable (beyond what individual DMs already do), I just can't imagine that we'll all truly be playing the same game. Not to mention the (now) sacred cow of playing by the rules-as-written, which is an attitude I've personally seen escalate from the 3E era into dogma in the 4E era.
Ultimately, I don't really feel like the issues I have with the game have anything to do with a rule set. My biggest issues with it have to do with the player base and the attitudes and personalities I have to deal with to get a game going. If people continue to flame and name-call each other into the 5E era, no awesome new edition will unify the fans or do much of anything to make my play experience better. Ultimately, I wonder how much effect a new edition will really have on people and their preferences.
All that being said, I fully intend to give the new edition a fair shake. I'll certainly do free playtesting and I'll certainly buy books if it's a game that I enjoy and can find players for.