Here's what I'm considering in the most basic terms.
The setting is part post-apocalytpic, part dark future.
The world was not completely destroyed during the apocalypse (the nature of which I have not settled on, but it will be something more insidious than all-of-a-sudden)... but a majority of the world was set back significantly. There will be areas of high radiation, dangerous, lawless places called the Wasteland (even though these are not necessarily contiguous areas, they are collectively called the Wasteland).
The cities that survived became self-contained arcologies, and the cities close to each other (for example LA and San Diego, Minneapolis and St. Paul, the NYC area) became even bigger arcologies. Within these arcologies, The Machine reigns supreme. The Machine is the collected Robotica, all self-aware machines, interconnected through the Net, whose main goals are to maintain control and gain control of more things. At the left hand of The Machine are the six MegaCorps that comprise 90% of the world's economy.
So I'm thinking Progress Level 6 for the most part, though there will be some mix of PL 5 (in the Wasteland) and PL 7 (restricted to the wealthy and connected within the MegaCorps and The Machine). There'll be mutants, cyborgs, purestrain humans, robots, martial arts, lasers, and all sorts of fun.
I'll present more of the rules stuff, and some expanded setting information, sometime soon. What I need from interested parties is what sort of characters you'd like to play in such a setting, so that I can get an idea of what sort of game to run. There's a lot of possibilities at this point, and I'd like to focus my efforts on what material we'll actually be using.
I do not need statted characters at this point. What I need are basic character concepts, and what role you'd like to play in this setting. Once we have a simple majority of one sort of game, I'll start a recruitment thread and make the call for actual characters.