shilsen said:As Brain said, since the sphere breaks line of effect, the spellcaster can only cast spells on himself and within the area of the sphere (and any spells that do not need line of effect).
It is essentially a straight, unblocked path between the caster and the point where he wants the spell to take effect. With certain caveats that are too long for me to cover here. Check the definition on pg.176 of the PHB for details. Most spells other than those with a Personal or Touch range need line of effect, but there's no consistent formula to it that I know of.ARandomGod said:What spells to not need line of effect, and or what is the exact definition of Line of Effect?