"You feel wet drops on your arm. Intelligence tells you that it's raining; Wisdom tells you to seek shelter."
-one of the old Basic D&D books, can't remember which one
So I'd say that a character with high INT and low WIS would be like a naïve PHD student who has earned multiple advanced degrees at a prestigious university, but has no real-world experience and has lived a very sheltered life. All "book smarts" with no "street smarts."