There are many I like, and of course your race and class are big factors... That said:
Heroic tier:
The good:
-
Armor Proficiency feats (+1 AC with a feat is a pretty good deal for most classes - if you can swing the ability requirements)
-
Blade Opportunist (combined with Polearm Gamble and a Glaive, yummy)
-
Dwarven Weapon Training and
Eladrin Soldier (retrain to Weapon Focus during paragon levels)
-
Improved Initiative and
Quick Draw
-
Lost in the Crowd (this feat alone makes me want to play a halfling)
- All the "
initiate" multiclass feats (extra skill AND an extra power, yes please!)
-
Toughness (your increased hit points also increase your healing surge value!)
The bad:
-
Agile Hunter /
Precise Hunter (way too situational)
- Pretty much all
Channel Divinity feats (the original abilities of both cleric and paladin are already pretty good)
-
Distracting Shield (the only high Wis fighters are the ones with polearms, who can't use shields - huh?)
-
Group Insight (aren't half-elves bad enough already?)
-
Sure Climber (one of those thematic but generally useless feats)
The interesting:
- I think
Powerful Charge has potential. Charging gives you a lot of extra movement and +1 to the attack roll, and Powerful Charge gives +2 to the attack. Even a basic melee attack becomes quite scary!
Paragon tier:
The good:
-
Armor Specialization (or, even better,
Shield Specialization)
-
Danger Sense
-
Dwarven Durability
-
Hammer Rhythm
-
Heavy Blade Opportunity
-
Scimitar Dance
-
Spell Focus (you really, really want this if you're a wizard)
The bad:
Actually I don't think there are any really bad feats here, but some of them are perhaps too situationally beneficial, like
Running Shot or
Sweeping Flail. It's obvious that the feats have been designed to specifically cater to certain types of characters, so most are useless to most, but precious to the few.
The interesting:
-
Back to the Wall supports strategic gameplay and gets a thumbs-up from me. The bonuses might be situational and minor, but my longspear-fighter will surely try to get those bonuses whenever she can!
-
Combat Anticipation - somewhat situational bonuses, but I hate all those AoE-effects and ranged curses (when on the receiving end

), so I think this will be a sweet investment.
-
Polearm Gamble seems pretty good, but it might only be worth it vs. minions who are certain to fall to the lowly OA - good combo with Heavy Blade Opportunity though!
-
Second Implement: I think this is pretty sweet, but depends on whether you have been able to invest in the other "implement stats" at all...
Epic tier:
The good:
Pretty much all of the epic feats are great, but again only applicable to those who have the specific weapon etc. Of particular value are IMO
Spell Accuracy and
Irresistible Flame, which are really good if they're applicable to the character and his abilities.
The bad:
I don't think there are any bad epic feats - all of the feats are pretty awesome for those who can use them.
The interesting:
I think
Epic Resurgence and
Triumphant Attack are really cool because they make some of the most exciting moments of the game - rolling the 20 (or 19) - even more exciting.