I'm definitely hyped for Eldraine, looking forward to the set. And the mix of Fairy Tale and Camelot high Fantasy is definitely a draw, I could see a DnD campaign working here. But I'm interested in how a more alien plane would work. Unfortunately, WoTC has a habit of blowing up or radically altering their worlds. I'm more interested in Alara when they were separate shards. Or Mirrodin pre-New Phyrexia. Though, admittedly, a Tarkir campaign about bringing back the Khans and clans and overthrowing the Dragons would also intrigue me.
I also, have to admit, I'm intrigued at the idea of a merged Multiverse. On the MTG side, Post-Mending, it used to be that only Planeswalkers could planar travel, but the planar bridge from Kaladesh means that is no longer the case. Meanwhile, that was never the case on the DnD side, planar travel didn't need a Spark, places like Sigil exist.