Warren Ellis did just this in "Planetary"...
Pic 1;
FULL PAGE PANEL. Seven icons stand or sit in the center of their hidden complex, a room hewn from rock, chewed out from within the mountain. A bizarre gentlemen’s club, a drawing room of the gods.
Seven icons, living and breathing, torn out of pre-War literature and made real in a secret base inside an American mountain... (BRASS just entering)
DOC SAVAGE -- THE RENAISSANCE MAN - DOCTOR AXEL BRASS
The character is, obviously, Doc Savage, but with enough alterations to prevent lawsuits (as with all the boys below). RED hair cut very short, tanned, dressed like a hunter, white hunter, all in white...
(Ellis note 3/99: There was a fuller description of Axel Brass on a previous page of the script)
FU MANCHU -- THE INSCRUTABLE ORIENTAL - HARK
We’re not going to go the full Fu Manchu route with this guy. I want him dressed very simply, in a black suit, no tie, the only unusual point being his remarkably long, elaborately painted fingernails.
TOM SWIFT -- THE INVENTOR - EDISON
All-American genius boy grown up into a strapping lad, slim and hard; white t-shirt, blue jeans, gun holstered on his hip, the long white lab coat pushed behind the holster, goggles hanging around his neck, oil on his fingers. A gunfighter-mechanic, if you like... an inventor-adventurer.
TARZAN -- JUNGLE KING - "HIS LORDSHIP"
The English Lord raised by gorillas; tall, muscular, dressed in an fine English suit, shirt, waistcoat -- aristocratic -- a cravat of leopardskin betraying his childhood. Seated, perhaps, fingers steepled in front of him, eyes burning, savagery barely contained beneath the veneer of civilised man.
THE SPIDER -- THE MILLIONAIRE
Like The Shadow, only without supernatural powers, and far, far crazier. A genius, but possessed by the need to save the world. Batman with guns and no mood stabilisers. Long leather coat, slouch hat, guns visible. A Spider design down one breast of his longcoat, in grey against the black.
G-8 -- THE AVIATOR
Tan leathers, cracked and worn... old-style jacket, fur trim and all... the very epitome of the Thirties flyer.
OPERATOR 5 -- THE AGENT - "JIMMY"
The Secret Agent; a thin scar over one eye like Fleming’s Bond, American suit and tie (blue, like The Spirit’s?); shoulder holster under the jacket, perhaps shades sticking out of the breast pocket. Young, but sharp, knowledgable beyond his years...
[The "no Doc Savage lawsuit" was an admirable goal...I seem to recall that some legal rumblings ensued, however, and Doc Brass has kept a low profile ever since...]
I did a pitch for Marvel Comics a while back with a similar group, although we added an African-American Indy --- a brilliant scholar and linguist born 50 years too soon, he supported himself as a treasure hunter --- and a Mandrake/Blackstone master of the unknown.