BG3 is the first one of those that has really emerged into zeitgeist territory, though. Sure, there were great and fairly popular D&D video games before then, but those and the CRPG genre as a whole has still been largely regarded as niche.No.
There's been D&D video game hits since The Gold Box days. I can't think of one that has changed the tabletop in any significant way.
It may draw some folks into playing the tabletop, but they are separate experiences. We might see a spell or mechanic from the game, but certainly no change in the direction of the design of the tabletop.
Of course, I'm always wrong on these sort of prognostications for just about anything.
It's like with Final Fantasy and how VII did the same thing for JRPGs. Even though IV and VI were well known, that genre was still largely regarded as niche until VII came along.