Yes, because once we have made such a snapshot decision, we are more likely to defend it, even with somewhat irrational arguments than to reevaluate it.
That's not really my MO.
I've tried oysters and tuna many ways...but no matter how much I try, I can't stand my oysters raw, and only enjoy tuna as sushi/sashimi.
I knew from reading GURPS that it wasn't my game. Years of playing it hasn't changed my opinion one bit.
The difference between GURPS and 4Ed, in this instance, is that my experience with GURPS was in a group that played a lot of the game, giving me countless opportunities to try it out.
With 4Ed, there is not one person in my circle of (10+) gamers who is willing to run it. There were differing main reasons for rejecting it: mine, oft described elsewhere on the board; some who feel personally and financially invested in 3.X, so don't want to change; the programmers (including game programmers) who felt it was too videogamey; those who didn't have the time or inclination to learn a new system...IOW, the gamut of reasons why people have cited for not playing 4Ed.
Btw, I would love to have this discussion in person. If you ever come to Ann Arbor, drop me a line and I will buy you a beer.
Man, I haven't been that far North in some time, and you're not the first to offer me a brewski if I head to the land of ice and snow.
I may just have to go on a trip across the northern reaches of the USA and Canada- or maybe arrange for us all to meet at GenCon*- to see how drunk I can get!

*one of these days, I WILL make it to GenCon.