He could fit in if it was an epic fate-of-the-multiverse type movie where for some reason he had to team up with his equivalents from other crystal spheres (ie. Mordenkainen, Raistlin Majere, etc.)
Trouble is there'd be absolutely no audience for that. 9/10 "Elminister-types" are pompous, self-regarding, smug, rude, disagreeable old men with bad beards, most of whom are sociopaths, and all of whom have terrible dress sense. Then you've Raistlin I guess standing next to them looking all emo and grimacing a lot.
It could work as a comedy, I guess, like a really broad comedy where they were clearly all idiots.
Minsc and Boo are interesting characters in their own right.
Oh come on, now you're just being silly.
Minsc is not an "interesting character". He doesn't have a personality. He's basically Magnitude from Community, there solely to say his catchphrase at appropriate moments. Instead of "Pop pop!" it's "Go for the eyes Boo!". Boo isn't a character at all. He's a pet. Who doesn't do anything. I love him but he's not someone you could tell a story about, because there's nothing to him (which is, ironically, part of why he's popular - most other BG characters have kind of annoying backstories/personalities).
But, but, but BUT! I would watch ten Minsc + Boo movies before I watched one Elminister movie, so I agree there. We can I think thank our lucky stars that Sean Connery is now way too old for the part or Greenwood would probably be basically camped outside WotC HQ trying to convince them to make that happen (there's like a clear moment in late 2E or early 3E when Elminister suddenly shifts to obviously being played by Sean Connery).
The FR doesn't really have a lot of workable characters who are also popular with the readers/players.
Drizzt would be an obvious choice (starting AFTER he left the Underdark and was well clear of the BDSM/slavery/etc.) but I just dunno if WotC wants to engage with something that, on-screen, will be as "problematic" as Drow. In animated feature, sure, you can make them very dark grey (an inhuman colour) and with inhuman features, but with actual human actors? Hmmmmmm. Maybe you could manage it but you're teetering on the edge of blackface (I know some people just don't get this "That's what Drow look like!", and bless their hearts, but they have no useful input if they don't get it), and for what gain? So I think he'll stay in games (and/or animated stuff). Especially with Jarlaxle who makes the whole "blackface" angle so much worse by insisting on literally dressing like a pimp.
I mean, people like Alias (inc. Dragonbait and so on) or Shandril (the spellfire lady) could work too, but does anyone even remember or care about them (I mean, I do re: Alias but I suspect very few people do).