I guess I fall in the middle somewhere...
I hate the idea of pre-selected loot tailored exactly to what each PC needs; however, since I'll be running e6 next campaign, so PCs will never get "godly" powerful, they won't need tons and tons of magic items, either.
I'm planning to be fairly generous with potions, scrolls, wands and minor wondrous items; even minor magic weapons and armor will not be too hard to come by, via swapping with traveling merchants, commissioning items, making requests from the local merchant, etc...
More powerful items (ie +2 weapons and armor, rings and moderate powered wondrous items) will either be unique items found in the hands of NPCs and have to be won/purchased/stolen, or will be crafted for PCs as rewards for specific quests. For example, there's a crafter-wizard in the campaign who has stated that she desires to establish herself in business in this town, but lacks capitol to do so. If the PCs bankroll her, she can become their own source of many custom items. Then again, she does have this strange snake tattoo on her wrist...
It'll be fun to see what happens.
I've NEVER thought PCs HAD to have the "big six". It's up to you as DM to balance the challenges the PCs face to what they have as items. If they lack +3 weapons, then be judicious in the monsters they face. It really is your campaign to run the way you want to run it.