Special Snowflake answer-
Blackmoor Gonzo? Sure
Barrier Peaks? Sure.
EPT? Sure
Starport? (13A)? Sure,
Arduin? Much of it is pushing too far for my tastes. Which has always made it a Love/Hate affair for me.
I think encountering the Gonzo in the typical D&D world as unique/isolated/rare thing is fine/fun/a change of pace and I use it as a DM.
When the Gonzo becomes the norm of the D&D world , Like say Technos and other elements in Arduin or Eberron's magical tech, or even Planescape- then I'm not a fan. I'd just rather run something like RIFTS.
That's my bag too- the Gonzo has to be neat-neat and mostly unexpected, leaving the players with a wry smile rather than trying to make them LOL.
My example would be in a run through of Elemental Evil the guys had a cart full of Pitchblende (they'd played through Lost Mines earlier- the stuff was mined there, this after hey had cleared out the bad guys and left the Dwarven folk in charge).
Anyway, long story short- the Pitchblende was the rocket fuel needed to power up the Dwarven Spaceship to go fetch Moradin from the heavens to fight the good fight against the Princes of Elemental Evil.
For three quarters (more. approx. 90%) of the adventure the only Gonzo was the Pitchblende (the Players eventually decided to look it up, for a good while they thought it was just high grade coal- because that's what I told 'em), and a door that they couldn't open that was quite definitely not from the fantasy milieu- sirens, hydraulics/magnetics/electrical power, with extra flashing lights- think military industrial complex meets Dwarf-mined-mithril and you're about there.
The only real Gonzo was the last ditch space dash and the Kirk to bridge cajolery in which the PCs had to persuade starman (Dwarf) Moradin to come on down with his space-hammer.
Memorable, rather than a different game/setting heaped on top of D&D.
Oh, in another campaign I DMed the players found a pair (eventually- they found one, and then maybe ten sessions later, the second) of modern day walkie-talkies (and not the D&D magic item equivalent- Sending Stones, from memory). They had fun with those bad boys- for like the best part of a year (real time), then came the pay off... turned out there was a third walkie-talkie and someone listening in, I think I waited something like 25+ sessions before creeping them out with that sucker.
So, Gonzo when the Gonzo is good.
It's a rule for life.
Cheers goonalan