I was thinking about it.

Heres what I have so far: (My players, stay out or be spoiled!)
[sblock]Algol, the Demon star, deep within the Ort Cloud, has had a mad revelation! If he absorbs all of the 'lesser' gods on all the worlds in the universe he will have enough power to consume the Demiurge when it awakens and rule the entire universe! But first, he needs a plan... The voices in his head told him to kidnap all the high-level mages from numerous worlds (faerun included) and replace them with Psuedonatural Dopplegangers. Then, gather all the great minds into one insane collective (a Cogent) to build Plutonium Golems like an assembly line. He will then use the army of Plutonium Golems to siege world after world, destroying the populace, and thusly, the deities on that world will be weakened, which is when he will strike and absorb them into his being effortlessly. A Cunning plan indeed; Those voices in his head sure are smart!
With his cosmic powers he has contacted Cyric, promising him candy and the souls of all Toril to rule over in exchange for a small 'favor': For Cyric to go about systematically slaying as many lesser gods as he can, and then allowing the newly created Un-Elementals to become tainted with Far Realm energies, which will likely result in even more chaos and dead gods!
The PCs will first need to unravel the mystery of why Elminster & Co have been sitting around drinking tea for the last few months instead of meddling in peoples affairs like they usually do. Then, gods will start dieing, with the weak/pointless ones first. The numerous Un-Elementals will begin destroying Toril. A couple of Abominations, long since sealed away or forgotten, will take this oh so perfect opportunity to break free once their imprisoning deities die. End Result: PCs go on wild goose chases while Cyric goes hunting. PCs will eventually figure out what's what and beat the crap out of Cyric, who, like the sniveling coward he is, blabs out his deal with Algol, figuring that since he couldn't kill all the gods, the deal is off. Too bad no one told him about Algol's Legion of Plutonium Golems, led by a Plutonium Colossus!
PCs must stop this new glow-in-the-dark army, and then, with the aid of Mystra's magic, (or their own) travel to the Ort Cloud, find Algols factory of horrors, defeat god knows what monsters that lie within, do battle with the Cogent, and then flee before our big, radioactive friend realizes that factories building an army of magical constructs are not supposed to explode.
If the PCs fail, Algol attacks the realms directly, and the resulting battle between Algol and Ao causes the spellplague; If not, Ltheb, back from his winter vacation at the Akashic Library, causes the Spellplague out of sheer boredom.

[/sblock]
Nothing real serious...

Just an excuse to crack open the bestiary, stat up Cyric, and roll out some epic level combats.

No clue yet about how much Xp and Qp or anything like that. Ideally, the PCs walk out of the adventure greater gods (up from lesser) and should be intermediate after they mop up Cyric. (Who I'm only throwing together as an Intermediate god because 4 Lesser deities VS an Intermediate one plus minions seems like a fair but hard fight)