I believe that Orca's, maybe the entire cetacean order, (biological meaning) are sentient. Same could be said with the higher apes. Imagine an Orca's mind suddenly being dropped into New York City, inside a human body. The results would be catastrophic for anyone in contact with said Orca-Human, let alone the Orca-Human.
As a native and current New Yorker, a Orca-Human wouldn't phase NYC much at all.