What others mentioned:
I agree on the humans. I don't really care if it's balanced or unbalanced, it just feels wrong.
I can also guarantee we won't be playing the game with its present math. I don't particularly care, but the bonuses remain small enough that they get swallowed by the d20 and one of my players absolutely will not stand for that.
My take:
Most of the system just doesn't elicit strong emotions one way or the other, though. I don't need much to get me excited enough to pick up a game, but D&D Next isn't there yet.
The only class I was excited about was the old playtest sorcerer. Which is fine, because I mostly GM anyway.
The mechanic I was most excited about was advantage/disadvantage, but it's gotten baked in so many places it doesn't do what I wanted it to anymore. It also becomes cumbersome with the addition of multi-attacks.
They could put out monsters that are easy to run and engaging, but for right now I'd still be looking at tearing out the monsters and redoing them all, completely defeating the point of switching for me.
So it's not that there's a deal-breaker for me, really, just a deep lack of deal-makers.
Cheers!
Kinak