I'd go with a campaign I've been working on for a while now namely:
GI Joe/Action Force (using the Spycraft ruleset). I figure on having the players each have 3 characters and they pick the one best suited for each mission. XP goes in a pool for the 3 so you can either continually level up the same character (and face possibly having an under experienced pilot/driver/specialist when you need them), or level all 3 more slowly. Cobra are great villains, with a good variety of recurring "bosses" like Major Bludd, Copperhead, Overkill etc, right up to the leaders such as Dr. Mindbender, Baroness, Tomax & Xamot, and of course Cobra Commander at higher levels.
The campaign pretty much writes itself and I get to run the group through some of the high (and low) points of the various comic stories like the creation of Cobra Island, the siege of Springfield, Serpentor and the Coil, the Red Shadows, Destro's Iron Grenadiers, as well as Zartan and the Dreadnoks.
And the best bit is that most of my group (save one of them) have no idea about any of this stuff at all. Muahahahha!!