I think Greyhawk will be one. 5E already has GH pretty strongly woven into it, and the only thing we are really missing is an official setting book.
1) We have official WotC adventures set in FR, Ravenloft, and GH. GH is the only one without a setting book.
2) Two of the "Guide" books are named after GH characters.
3) GH is one of the four pantheons described in the PHB (two of the others - FR and Eberron - have their own setting books).
4) GH was created by Gary Gygax and was the first official D&D setting. With Saltmarsh and TftYP Wizards talked about wanting newer players have a continuity of experience with older generations of players. No setting serves that interest better than GH.
The main counterargument to GH has always been that it fills the same niche as FR. And that was a good argument when we only had a couple of setting books out. But with Stryxhaven we are going to have what, seven(?) official setting books with four or five more in some stage of development. At this point it is hard to argue we can't have two that fill the "standard D&D assumptions" role.
1) We have official WotC adventures set in FR, Ravenloft, and GH. GH is the only one without a setting book.
2) Two of the "Guide" books are named after GH characters.
3) GH is one of the four pantheons described in the PHB (two of the others - FR and Eberron - have their own setting books).
4) GH was created by Gary Gygax and was the first official D&D setting. With Saltmarsh and TftYP Wizards talked about wanting newer players have a continuity of experience with older generations of players. No setting serves that interest better than GH.
The main counterargument to GH has always been that it fills the same niche as FR. And that was a good argument when we only had a couple of setting books out. But with Stryxhaven we are going to have what, seven(?) official setting books with four or five more in some stage of development. At this point it is hard to argue we can't have two that fill the "standard D&D assumptions" role.