UngeheuerLich
Legend
I don't feel like you understood the premise, which is probably my fault for being unclear: the assumption by everyone at the table going in is that the combat challenges in the game (however the come about) will be the only one for the "day" (between long rests) and it is presumed that PCs will be able to unload without concern over whether they will not have anything left in the tank for the next fight because there explicitly will not be one before the next rest. So, given that, what are the consequences and considerations, both fore the GM on the design side and for the players.
In 5e as is?
Tell this you players before chosing character classes, as the only viable ones are full casters.
Every other class will suffer because of limited nova capabilities. The only non full caster that might have a small chance to be semi capable could be the paladin.