Here's the thing; folks are talking about Central CA like it isn't full of genuine cities. And they aren't wrong, but most places in Central CA are a hell of a lot closer to "somewhere" than where I'm at.
Our largest city is 30,000 strong. It's about a three mile drive to Redding along one of the worst highways in America, which is the closest you can get to something pushing six digit population. We have two roads out of our area, East on the 299 (the aforementioned crap road to Redding), and the 101 heading north (single lane) and south (two lanes, mostly). All three are prone to closures during extreme weather, especially from rock slides. We have literally been trapped in the area before.
We're about six hours north of the Bay Area, when the road is open anyway, and about two hours south of the Oregon border.
You don't get more middle of nowhere in CA than Humboldt.