It's brought a crapton of lousy 3PP supplements that nearly killed off the FLGS as an industry.
The FLGS is always dying. It's a marginal business at best. Moreover, I've never seen a FLGS that sold only RPGs; most of them seem to make most of their money off board games, Magic, Warhammer, etc. If everyone suddenly stopped playing RPGs over the next few years, my FLGSs would simply phase out the couple of shelves of RPGs for more board games, etc.
It's brought a number of what would have otherwise been unpublishable piles of drivel and given them access to a depraved market segment that does the industry a major disservice by their very existence. (Fatal being a relatively tame example thereof. Worse exists.)
What does Fatal have to do with the OGL? I have no clue how the OGL has anything to do with any of that, unless you're blaming the existence of small publishers and DriveThruRPG on the OGL. Maybe not DriveThruRPG, but if you're not a big publisher, and not on DriveThruRPG or maybe Paizo or E23, then you're in your own backwoods, where I'm pretty sure that's always been publishable on the Internet and you can use GURPS, D&D, whatever, and the odds anyone will ever notice is minimal.
It's caused some really good publishers to pick really sexualized art in order to stand out enough from the drivel to get noticed. (Avalanche Press, anyone?)
You are responsible for your own actions. If a publisher uses sexualized art to stand out, then it's their own fault.
It's lead some publishers to take bigger risks with licensed properties than they should because they count on the open licensed rules' popularity.
Again, you are responsible for your own actions. If a publisher misjudges the market, that's their own fault. I see absolutely no reason to think that the OGL changed this at all; there's been lots of flash in the pan licensed works, and a lot of companies having trouble with licenses, long before the OGL.
It's also lead some publishers to not make needed adaptations because they don't want to lose the fans of whatever system they're basing upon.
So it's better for them to be using an ad-hoc system that they're constantly changing because the fans aren't in love with the rules, instead of a system that the fans are in love with?
Tho' I do wonder what wonderful new stuff the Paizo crew would have done if they hadn't had the ability to essentially pirate D&D 3.5...
It's a shame that all the non-TSR people before the OGL were so uncreative then; it wasn't until Paizo that we had anyone who could create wonderful new stuff, and the bad, bad OGL sidelined them. Bah. More likely Paizo would have never existed without the OGL, or struggled along.