I think it's worth pointing out that Jeremy is only talking about humanoids. He's not talking about removing built-in alignments for other kinds of creatures, like fiends.
Dunno, and dammit I wasn't going to comment but now I can't help myself. So, I looked at my copy of
Tasha's and under
Summon Fiend (6th level conjuration), the demon you summon has no alignment. Not one creature mentioned in the entire book has an alignment.
I suppose this could be because its alignment doesn't matter when its under your total domination and enslavement. You could make the demon hug small children, hand out flowers, and kiss babies for an hour, or perform hard labor, or rip apart your enemies with all the fury that a demon brings.
But damn, demons aren't evil, is that where the end goal lies? I don't play D&D to gain my moral and ethical spectrum on the real world. I play it because it's fun to be the heroes in Lord of the Rings who fight overwhelming odds to save the world from the balrog that ripped itself from the depths of the hells to burn the world and everything in it, or the mutilated elves turned orcs who aren't going to be good guys no matter how many flowers you give them because they are manufactured aberrations, abominations, things created by darkness to be dark.
I play an elf because it intrigues me, and I don't get jealous when they don't have the same physiology as a dwarf. I don't complain that my human should be able to see in the dark because elves can, or that my 3 foot tall halfling isn't as strong as an ogre can be. If my character wants to see in the dark as a human, he'll work for it. He'll learn magic and cast the Darkvision spell, or quest for some magical glasses. If my small character has physics against him, he'll work for it. He'll find a different way to fight than the ogre does, or he'll quest for some magical gear to enhance his strength.