Well, in our group, we've often had to reschedule due to conflicts. But we set up an email list that lets us communicate. We've been through a few changes of persons, with players relocating (3 in all, 2 of the originals and one who was brought in to replace the first original player who left), but the game has gone on strong for the last year. And EVERYONE has always been eager to play. We've played D&D 3.5 and, more recently, Castles and Crusades. We even tried a session of Warhammer last week.
Of course, now our regular DM/CK for the past year, Enworld's own Akrasia, is departing for Ireland, leaving this group of gamers DMless. We'll probably adapt, as almost all of us have DMed in the past, but if you can make it up to Emeryville every week, I might have a group of eager gamers for ya.
Not that I'm recruiting or anything.
For what it's worth, the group originally coalesced thanks to the WotC boards, so we're a pretty gung-ho bunch of committed gamers. And yes, we have still had scheduling problems. For what it's worth, we usually play once a week on a weeknight, since people usually have more commitments on the weekends. It's been working so far.