I'm neutral on the layout. We had a standard style in the 2014 book, and while it made understanding the rules a bit easier (with the logical reading order), it made finding specific rules difficult. Learning the rules for 2024 is a bit harder, but I imagine they're going to be much easier to look up during play.
Definitely written with D&D Beyond in mind. I use Roll20, and I plan to create a rules glossary of handouts for my players by copy and pasting from Beyond. That way they have access to it without having to open Beyond.I would note that if viewed on D&D Beyond (where hyperlinking/hovering can pull up the appropriate rule without leaving the original text) it's a far superior experience. But getting used to the footnote style of reading the paper PHB takes some getting use to.